CEFIOFF Dry Syrup – Cefixime 50 mg + Ofloxacin 50 mg/5 mL Oral Suspension

CEFIOFF Dry Syrup by Amcare Pharmaceuticals is a prescription antibacterial combination containing Cefixime IP (as Trihydrate) equivalent to Anhydrous Cefixime 50 mg and Ofloxacin IP 50 mg per 5 mL of reconstituted suspension. It is supplied as a dry syrup with sterile water for reconstitution.

CEFIOFF Dry Syrup Composition

Each 5 mL of reconstituted suspension contains:

• Cefixime IP (as Trihydrate) equivalent to Anhydrous Cefixime – 50 mg
• Ofloxacin IP – 50 mg
• Excipients – q.s.
• Flavoured Base – q.s.
• Colour – Quinoline Yellow

CEFIOFF Dry Syrup Product Details

CEFIOFF Dry Syrup Uses

CEFIOFF Dry Syrup contains two antibacterial agents and should be used only when this combination is specifically prescribed for a susceptible bacterial infection.

Cefixime is a cephalosporin antibacterial, while ofloxacin belongs to the fluoroquinolone class. The choice of this combination, particularly in children, should be made by a qualified healthcare professional based on the infection, age, weight and individual risk factors.

CEFIOFF is not intended to treat viral infections, such as the common cold or influenza.

CEFIOFF Dry Syrup Benefits

• Contains Cefixime 50 mg + Ofloxacin 50 mg per 5 mL
• Two antibacterial agents with different mechanisms of action
• Convenient oral suspension formulation
• Supplied with sterile water for reconstitution
• Mango-flavoured formulation

How Does CEFIOFF Dry Syrup Work?

Cefixime in CEFIOFF

Cefixime is a cephalosporin antibacterial. It works by interfering with bacterial cell-wall synthesis, helping inhibit susceptible bacteria.

Ofloxacin in CEFIOFF

Ofloxacin is a fluoroquinolone antibacterial. It acts on bacterial enzymes involved in DNA replication and repair, thereby inhibiting susceptible bacteria.

CEFIOFF Dual Antibacterial Action

The formulation combines cefixime and ofloxacin, which act through different antibacterial mechanisms. This combination should be used only when considered clinically appropriate by the prescribing doctor.

CEFIOFF Dry Syrup Dosage and Administration

The dosage and duration of CEFIOFF Dry Syrup must be determined by a healthcare professional based on the patient’s age, body weight, type of infection, kidney function and clinical condition.

• Reconstitute according to the instructions on the product pack.
• Shake well before each use.
• Measure each dose accurately using an appropriate measuring device.
• Give only the quantity prescribed by the doctor.
• Complete the prescribed course unless the doctor advises otherwise.
• Do not self-medicate or use leftover antibiotics.

CEFIOFF Dry Syrup Side Effects

Possible side effects may include:

• Nausea
• Vomiting
• Diarrhea
• Abdominal discomfort
• Indigestion
• Headache
• Dizziness
• Skin reactions

Because the product contains ofloxacin, fluoroquinolone-associated serious adverse effects can include tendon injury, peripheral neuropathy and central nervous system effects. Seek medical advice promptly if unusual or severe symptoms develop.

CEFIOFF Dry Syrup Precautions and Warnings

Inform the prescribing doctor if the patient:

• Is allergic to cefixime, ofloxacin, cephalosporins or fluoroquinolones.
• Has kidney problems.
• Has a history of tendon problems.
• Has seizures or other neurological disorders.
• Has heart-rhythm problems.
• Has experienced severe antibiotic-associated diarrhea.
• Is taking other medicines.

Special caution is important in children because this formulation contains ofloxacin. It should be given only when specifically prescribed after medical assessment.

CEFIOFF Dry Syrup Storage

• Store according to the instructions provided on the product label.
• Protect the dry powder from excessive heat and moisture.
• After reconstitution, follow the manufacturer’s storage and discard instructions.
• Keep the bottle tightly closed.
• Keep out of reach of children.

Why Choose CEFIOFF Dry Syrup by Amcare Pharmaceuticals?

CEFIOFF Dry Syrup by Amcare Pharmaceuticals provides Cefixime 50 mg + Ofloxacin 50 mg per 5 mL in an oral suspension formulation supplied with sterile water for reconstitution.