ETORCAN-90 Tablets – Etoricoxib 90 mg Tablets

ETORCAN-90 Tablets by Amcare Pharmaceuticals contain Etoricoxib IP 90 mg, a selective cyclooxygenase-2 (COX-2) inhibitor belonging to the NSAID class. It is a prescription medicine used for the symptomatic management of pain and inflammation in conditions such as rheumatoid arthritis and ankylosing spondylitis, and etoricoxib is also used at indication-specific doses for osteoarthritis, acute gout and certain acute pain conditions.

Composition of ETORCAN-90 Tablets

Dosage form: Film-coated tablet
Strength: Etoricoxib 90 mg
Pack size: 10 × 10 Tablets
Category: Prescription NSAID / Selective COX-2 inhibitor
Manufacturer/Marketer: Amcare Pharmaceuticals

What are ETORCAN-90 Tablets used for?

ETORCAN-90 Tablets may be prescribed by a physician for the symptomatic relief of pain and inflammation associated with:

• Rheumatoid arthritis
• Ankylosing spondylitis
• Certain other inflammatory musculoskeletal conditions, depending on the prescribed dose and clinical indication
• Etoricoxib as a medicine is also indicated for osteoarthritis and acute gouty arthritis, although the appropriate strength and duration vary by condition.

The 90 mg strength should not automatically be considered appropriate for every pain condition. Etoricoxib dosing is indication-specific, and treatment should use the lowest effective dose for the shortest appropriate duration.

How Does ETORCAN-90 Work?

Etoricoxib

Etoricoxib selectively inhibits the COX-2 enzyme, which participates in the production of prostaglandins involved in pain and inflammation.

By reducing prostaglandin production, etoricoxib can help reduce:

• Pain
• Inflammation
• Joint discomfort
• Stiffness associated with inflammatory joint conditions

Because it is a selective COX-2 inhibitor, its pharmacological profile differs from that of traditional non-selective NSAIDs, but it still carries important gastrointestinal, cardiovascular, renal and blood-pressure-related risks.

Dosage & Administration

ETORCAN-90 Tablets should be taken strictly according to the physician’s prescription.

Etoricoxib is generally administered once daily, with or without food. The appropriate dose depends on the condition being treated. For example, current product information lists 60–90 mg once daily for rheumatoid arthritis or ankylosing spondylitis, with 90 mg being the maximum recommended daily dose for these conditions. Osteoarthritis generally uses lower doses, while acute gout has a different higher-dose short-course regimen.

Do not increase the dose or duration without medical advice.

Benefits / Therapeutic Role

When appropriately prescribed, ETORCAN-90 may provide:

1. Pain Relief

Helps reduce pain associated with inflammatory joint disorders.

2. Anti-inflammatory Action

Reduces prostaglandin-mediated inflammatory activity.

3. Joint Symptom Management

May help improve pain-related limitations and stiffness associated with inflammatory arthritis.

4. Once-Daily Administration

Etoricoxib is designed for once-daily administration for its approved indications, making it convenient when prescribed appropriately.

Possible Side Effects

Common or clinically relevant adverse effects can include:

• Stomach discomfort
• Indigestion
• Nausea
• Headache
• Dizziness
• Swelling/edema
• Increased blood pressure
• Fatigue
• Changes in liver enzymes

Etoricoxib can also cause more serious reactions, including gastrointestinal ulceration or bleeding, kidney problems, cardiovascular events, severe allergic reactions and serious skin reactions.

Seek immediate medical attention if you experience:

• Chest pain or difficulty breathing
• Sudden weakness or speech difficulty
• Black/tarry stools or vomiting blood
• Severe allergic reaction or facial/throat swelling
• Severe skin rash, blistering or peeling
• Significant reduction in urine output
• Severe or persistent abdominal pain

Precautions & Warnings

ETORCAN-90 should be used only after appropriate medical assessment.

Cardiovascular Risk

Etoricoxib may increase cardiovascular risk, particularly with higher doses and longer treatment durations. Patients with cardiovascular risk factors such as hypertension, diabetes, smoking or high cholesterol require careful medical consideration.

Blood Pressure

Etoricoxib can cause or worsen hypertension. Blood pressure should be adequately controlled before treatment and monitored during therapy.

Stomach & Intestinal Risk

Although etoricoxib is COX-2 selective, serious gastrointestinal complications such as ulcers, bleeding and perforation can occur. Risk may increase when combined with aspirin or other NSAIDs.

Kidney Function

Patients with kidney impairment, dehydration, heart failure or other conditions affecting renal blood flow require particular caution. Etoricoxib is contraindicated in severe renal impairment with creatinine clearance below 30 mL/min according to the cited product information.

Liver Function

Patients with liver disease may require dose limitations or should avoid etoricoxib in severe hepatic impairment.

Who Should Avoid ETORCAN-90?

Etoricoxib is contraindicated or unsuitable in certain patients, including those with:

• Active stomach ulcer or gastrointestinal bleeding
• Severe liver disease
• Severe renal impairment
• Uncontrolled hypertension
• Certain types of heart disease
• Previous heart attack or established ischemic cardiovascular disease
• Peripheral arterial disease or cerebrovascular disease
• Certain NSAID/aspirin hypersensitivity reactions
• Inflammatory bowel disease
• Pregnancy
• Children under 16 years, according to the cited product information

A doctor should review the patient’s medical history before prescribing this medicine.

Drug Interactions

Tell your doctor if you are taking:

• Warfarin or other oral anticoagulants
• Aspirin
• Other NSAIDs
• ACE inhibitors such as enalapril
• ARBs such as losartan
• Diuretics
• Lithium
• Methotrexate
• Digoxin
• Cyclosporine or tacrolimus
• Rifampicin
• Certain hormonal contraceptives or hormone replacement therapy

Etoricoxib can affect blood pressure, kidney function or the levels/effects of some medicines. Warfarin users may require INR monitoring. Combining etoricoxib with other anti-inflammatory NSAIDs is generally not recommended.

ETORCAN-90 During Pregnancy & Breastfeeding

Etoricoxib should not be used during pregnancy according to the cited product information. It is also contraindicated during breastfeeding in that product information. Women planning pregnancy should discuss NSAID/COX-2 inhibitor use with their healthcare professional.

Driving & Operating Machinery

Some patients may experience dizziness, vertigo or drowsiness while taking etoricoxib. Patients experiencing these effects should avoid driving or operating machinery.

Storage

Store ETORCAN-90 Tablets:

• In a cool, dry place
• Away from direct sunlight
• Away from excessive moisture
• Out of reach of children

Follow the storage conditions printed on the final approved product packaging.

Key Product Features

• Brand: ETORCAN-90
• Active ingredient: Etoricoxib
• Strength: 90 mg
• Dosage form: Film-coated tablets
• Therapeutic class: Selective COX-2 inhibitor / NSAID
• Pack: 10 × 10 Tablets
• Company: Amcare Pharmaceuticals
• Prescription medicine: Yes

Why Choose ETORCAN-90 by Amcare Pharmaceuticals?

ETORCAN-90 is a pharmaceutical formulation containing Etoricoxib IP 90 mg for physician-directed management of appropriate pain and inflammatory conditions.

Amcare Pharmaceuticals focuses on pharmaceutical products across multiple therapeutic segments, with an emphasis on quality-focused product development and professional healthcare distribution.