Amcare Biosciences

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Mico GM®

Product Composition

Manufacturer of Clobetasol Propionate IP 0.05 % w/w Neomycin IP 0.5 % w/w Miconazole Nitrate I.P 2.0% w/w

Packaging Details

20 X 30 gm

Product Description

Mico GM Cream – Complete Product Information

Mico GM Cream by Amcare Pharmaceuticals is a topical combination cream containing Clobetasol Propionate, Neomycin Sulphate and Miconazole Nitrate. The formulation combines a potent topical corticosteroid with an antibacterial and antifungal agent.

According to the supplied product artwork, Mico GM Cream is indicated on the pack “for mixed secondary infections in dermatoses.” Because it contains clobetasol propionate 0.05%, a very potent topical corticosteroid, it should be used under appropriate medical supervision and for the duration prescribed.


1. Mico GM Cream Composition

The following composition is transcribed from the supplied product artwork:

Ingredient Standard Strength
Clobetasol Propionate IP 0.05% w/w
Neomycin Sulphate IP Equivalent to Neomycin 0.5% w/w
Miconazole Nitrate IP 2.0% w/w
Chlorocresol IP 0.1% w/w
Cream Base — q.s.

Active Ingredients

Clobetasol Propionate 0.05% w/w
A very potent topical corticosteroid used to reduce inflammation, redness and itching.

Neomycin Sulphate equivalent to Neomycin 0.5% w/w
A topical aminoglycoside antibiotic active against susceptible bacteria.

Miconazole Nitrate 2.0% w/w
An imidazole antifungal agent used against susceptible fungi.

Chlorocresol 0.1% w/w
Used as a preservative in the cream formulation.


2. Product Details

Product Information Details
Brand Name Mico GM
Generic Name Clobetasol Propionate + Neomycin + Miconazole Nitrate
Dosage Form Cream
Route Topical / External application
Pack Size 30 g
Therapeutic Category Topical corticosteroid + antifungal + antibacterial combination
Company Amcare Pharmaceuticals
Pack Indication For mixed secondary infections in dermatoses

3. What Is Mico GM Cream Used For?

Mico GM Cream contains three pharmacologically active therapeutic components with different actions.

Mixed Secondary Skin Infections

The product artwork describes Mico GM Cream as being intended for mixed secondary infections in dermatoses.

Such conditions may involve inflammatory skin disease complicated by fungal and/or bacterial infection. However, the exact diagnosis should be established by a healthcare professional before treatment.

Fungal Component

Miconazole nitrate provides antifungal activity against susceptible fungi.

Bacterial Component

Neomycin provides antibacterial activity against susceptible bacteria.

Inflammatory Component

Clobetasol propionate reduces inflammation, redness and itching associated with responsive dermatoses.

Important

Mico GM should not be considered a general-purpose cream for every itchy or fungal skin condition. The presence of clobetasol means that inappropriate or prolonged use can mask infection and produce corticosteroid-related adverse effects.


4. How Does Mico GM Cream Work?

The three therapeutic ingredients work through different mechanisms.

Clobetasol Propionate – Anti-inflammatory Action

Clobetasol is a very potent topical corticosteroid. It suppresses inflammatory responses in the skin and helps reduce:

  • Redness
  • Swelling
  • Inflammation
  • Itching

It does not directly kill fungi or bacteria.

Miconazole Nitrate – Antifungal Action

Miconazole interferes with fungal ergosterol synthesis, affecting the structure and function of susceptible fungal cell membranes.

Neomycin – Antibacterial Action

Neomycin is an aminoglycoside antibiotic that interferes with bacterial protein synthesis, helping inhibit susceptible bacteria.

Chlorocresol – Preservative

Chlorocresol is included as a preservative to help maintain the microbiological quality of the cream formulation.


5. Mico GM for Fungal Skin Infections

Miconazole nitrate provides antifungal activity against susceptible fungi.

Fungal skin infections can produce symptoms such as:

  • Itching
  • Scaling
  • Redness
  • Burning
  • Skin discoloration
  • Localized patches

However, not every itchy or scaly skin lesion is fungal.

The presence of clobetasol in Mico GM requires particular caution. A potent corticosteroid can reduce visible inflammation while potentially allowing an untreated fungal infection to persist or spread.

Therefore, the product should be used for fungal involvement only when the prescribing healthcare professional considers the combination appropriate.


6. Mico GM for Bacterial Skin Infections

Neomycin provides antibacterial activity against susceptible organisms.

A secondary bacterial infection can occur in some inflammatory skin conditions, particularly when the skin barrier has been damaged.

However, not every red or inflamed skin lesion is bacterial. Unnecessary topical antibiotic use can contribute to antimicrobial resistance and may also cause allergic contact dermatitis in susceptible individuals.


7. Mico GM for Inflammation and Itching

Clobetasol propionate is included to control inflammatory symptoms.

It can provide relief from:

  • Redness
  • Itching
  • Swelling
  • Inflammation

Because clobetasol is a very potent corticosteroid, it should generally be used for the shortest appropriate duration and only on the area directed by the prescriber.


8. Dosage and Administration

The appropriate application frequency and duration depend on the patient’s diagnosis, affected body area, severity and clinical response.

General application instructions

  • Apply a thin layer to the affected area as directed by the physician.
  • Use only the prescribed amount.
  • Do not apply more frequently than instructed.
  • Avoid contact with eyes and mucous membranes.
  • Do not cover the treated area with an airtight dressing unless specifically instructed.
  • Wash hands after application unless the hands are being treated.
  • Do not continue treatment beyond the prescribed duration.

Because Mico GM contains clobetasol propionate 0.05%, prolonged self-use should be avoided.


9. How to Apply Mico GM Cream

  1. Clean and gently dry the affected area if instructed.
  2. Apply a thin layer of Mico GM Cream to the affected skin.
  3. Gently spread the cream without excessive rubbing.
  4. Wash your hands after application unless the hands are the treatment area.
  5. Follow the exact frequency and duration prescribed by the doctor.

Do not share the cream with other people or use it for a different skin condition without medical advice.


10. Side Effects of Mico GM Cream

Topical side effects can occur, particularly with prolonged use or application to sensitive areas.

Possible Local Side Effects

  • Burning or stinging
  • Skin irritation
  • Redness
  • Dryness
  • Itching
  • Allergic reaction
  • Contact dermatitis

Corticosteroid-Related Effects

Prolonged or inappropriate use of clobetasol may cause:

  • Skin thinning
  • Stretch marks
  • Visible small blood vessels
  • Changes in skin pigmentation
  • Delayed wound healing
  • Increased susceptibility to infection
  • Masking or worsening of an underlying infection

Neomycin-Related Sensitivity

Neomycin can cause allergic contact dermatitis in some individuals, particularly with repeated topical exposure.

Seek Medical Advice If

  • The condition becomes worse.
  • The infection spreads.
  • Severe irritation develops.
  • Significant swelling occurs.
  • The skin becomes unusually thin.
  • Symptoms persist despite treatment.

11. Precautions and Warnings

Before using Mico GM Cream, inform your doctor if you have:

  • A suspected or confirmed fungal infection
  • A bacterial skin infection
  • Viral skin infection
  • Broken skin or open wounds
  • A history of allergy to neomycin
  • A history of allergy to any component of the formulation
  • Acne or rosacea
  • A skin condition affecting the face
  • A condition requiring treatment over a large body area
  • A requirement for prolonged corticosteroid treatment

Use on the Face

Particular caution is required when using clobetasol-containing preparations on the face because facial skin is more susceptible to corticosteroid-related adverse effects.

Skin Folds

Extra care is required when applying potent corticosteroids to areas such as:

  • Groin
  • Armpits
  • Other skin folds

Use in these areas should be specifically directed by a healthcare professional.


12. Mico GM and Drug Interactions

Systemic drug interactions are generally less likely with limited topical application than with oral medicines. However, risk may increase when potent topical corticosteroids are applied over large areas, under occlusion or for prolonged periods.

Tell your doctor or pharmacist about:

  • Other topical corticosteroids
  • Other antifungal creams
  • Other topical antibiotics
  • Other medicated skin preparations
  • Any known allergies to topical medicines

Do not combine multiple medicated creams on the same skin area unless instructed by a healthcare professional.


13. Mico GM During Pregnancy

The safety of the complete combination during pregnancy should be assessed by a healthcare professional.

Because Mico GM contains clobetasol propionate, particular caution is appropriate, especially with prolonged treatment, application over large areas or use under occlusion.

Do not start Mico GM during pregnancy without medical advice.


14. Mico GM During Breastfeeding

Consult your doctor before using Mico GM while breastfeeding.

Avoid applying the cream to the breast or nipple area where it could come into direct contact with the infant unless specifically instructed by a healthcare professional.


15. Who Should Not Use Mico GM Without Medical Evaluation?

Mico GM should not be self-medicated for:

  • Undiagnosed itching
  • Any unexplained skin rash
  • Routine fungal infections without diagnosis
  • Acne
  • Rosacea
  • Viral skin infections
  • Open wounds
  • Unexplained ulcers
  • Long-term maintenance of skin conditions

People with known hypersensitivity to any ingredient should avoid the product unless a healthcare professional has evaluated the situation.


16. Key Features of Mico GM Cream

1. Triple Therapeutic Combination

Contains:

  • Clobetasol Propionate
  • Neomycin
  • Miconazole Nitrate

2. Antifungal Component

Miconazole Nitrate 2% w/w provides antifungal activity against susceptible fungi.

3. Antibacterial Component

Neomycin equivalent to 0.5% w/w provides antibacterial activity against susceptible organisms.

4. Potent Anti-inflammatory Component

Clobetasol Propionate 0.05% w/w helps control inflammatory symptoms.

5. Preservative

Chlorocresol 0.1% w/w is included as a preservative.

6. Convenient 30 g Pack

The supplied product artwork shows a 30 g cream pack.


17. Why Choose Mico GM by Amcare Pharmaceuticals?

Mico GM Cream provides a combination of:

  • Clobetasol Propionate IP 0.05% w/w
  • Neomycin equivalent to 0.5% w/w
  • Miconazole Nitrate IP 2.0% w/w
  • Chlorocresol IP 0.1% w/w
  • Cream base q.s.
  • Topical cream formulation
  • 30 g pack size

The packaging describes the product as intended for mixed secondary infections in dermatoses.

The product should be used according to the diagnosis and prescribing instructions of a qualified healthcare professional.

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Besides Changodar Bridge, Changodar, Ahmedabad-382213.

+91 99139 17125

info.amcerebiosciences@gmail.com

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