Moxymul CV 228.5 – Amoxicillin 200 mg + Clavulanic Acid 28.5 mg Dry Syrup

Moxymul CV 228.5 by Amcare Pharmaceuticals is an oral antibacterial suspension containing Amoxicillin 200 mg + Clavulanic Acid 28.5 mg per 5 mL of reconstituted suspension. It is supplied as a dry syrup and is intended for pediatric use when prescribed by a qualified healthcare professional.

Amoxicillin is a penicillin-class antibacterial, while clavulanic acid inhibits certain beta-lactamase enzymes that can reduce the effectiveness of amoxicillin. The 200 mg/28.5 mg per 5 mL strength is an established amoxicillin/clavulanate oral-suspension formulation.

Composition of Moxymul CV 228.5

Each 5 mL of reconstituted suspension contains:

• Amoxycillin Trihydrate I.P. equivalent to Amoxycillin — 200 mg
• Potassium Clavulanate Diluted I.P. equivalent to Clavulanic Acid — 28.5 mg
• Excipients — q.s.
• Flavoured Base — q.s.

Moxymul CV 228.5 Product Details

The official prescribing information recognizes 200 mg/28.5 mg per 5 mL as a dosage strength of amoxicillin/clavulanate oral suspension.

Moxymul CV 228.5 Uses

Amoxicillin/clavulanate oral suspension is indicated for susceptible bacterial infections, including:

• Lower respiratory tract infections
• Acute bacterial otitis media
• Bacterial sinusitis
• Skin and skin-structure infections
• Urinary tract infections

These indications are for susceptible bacterial organisms and should be determined by the prescribing healthcare professional. Antibiotics should be used when a bacterial infection is proven or strongly suspected.

Lower Respiratory Tract Infections

Moxymul CV 228.5 may be prescribed for certain susceptible bacterial infections affecting the lower respiratory tract.

Acute Bacterial Otitis Media

Amoxicillin/clavulanate is used for certain bacterial middle-ear infections, particularly where susceptible beta-lactamase-producing organisms are involved.

Bacterial Sinusitis

The combination may be prescribed for susceptible bacterial sinus infections.

Skin and Skin-Structure Infections

It may be used for certain susceptible bacterial infections involving the skin and related structures.

Urinary Tract Infections

Amoxicillin/clavulanate has labelled use for certain susceptible bacterial urinary tract infections.

Benefits of Moxymul CV 228.5

• Contains Amoxicillin 200 mg + Clavulanic Acid 28.5 mg per 5 mL.
• Pediatric oral-suspension formulation.
• Dry syrup format allows reconstitution before administration.
• Flavoured base helps provide a child-oriented oral dosage form.
• Clavulanic acid helps inhibit certain beta-lactamase enzymes.
• Provides antibacterial activity against susceptible bacteria.

How Does Moxymul CV 228.5 Work?

Amoxicillin 200 mg

Amoxicillin is a penicillin-class antibacterial that interferes with bacterial cell-wall synthesis, inhibiting the growth of susceptible bacteria.

Clavulanic Acid 28.5 mg

Clavulanic acid is a beta-lactamase inhibitor. It inhibits certain bacterial beta-lactamase enzymes, helping protect amoxicillin from enzymatic degradation and extending the activity of the combination against certain beta-lactamase-producing bacteria.

Moxymul CV 228.5 Dosage & Administration

Moxymul CV 228.5 should be administered to children only according to the dose prescribed by a qualified healthcare professional.

Pediatric dosing may depend on:

• Child’s body weight
• Age
• Type and severity of infection
• Kidney function
• Susceptibility of the causative organism
• Clinical response

The official labeling calculates pediatric dosing based on the amoxicillin component, rather than simply using the combined strength.

Do not change the prescribed dose or duration without consulting the doctor.

How to Prepare Moxymul CV 228.5 Dry Syrup

The product shown is supplied as a dry syrup with sterile water.

For preparation:

1. Follow the reconstitution instructions supplied with the product.
2. Add the specified amount of sterile water as directed.
3. Close the bottle and shake thoroughly.
4. Ensure the powder is adequately dispersed.
5. Use the reconstituted suspension only as directed by the healthcare professional.
6. Shake the suspension well before each administration.

The exact quantity of water and storage period after reconstitution should follow the product’s approved label/package instructions.

Moxymul CV 228.5 Side Effects

Possible adverse effects associated with amoxicillin/clavulanate include:

• Diarrhea
• Nausea
• Vomiting
• Skin rash
• Abdominal discomfort

More serious reactions, including severe allergic reactions, severe skin reactions, liver dysfunction and antibiotic-associated diarrhea, can occur.

If a child develops difficulty breathing, facial swelling, severe rash, persistent/severe diarrhea, jaundice or other serious symptoms, seek medical attention promptly.

Moxymul CV 228.5 Precautions & Warnings

• Do not use in patients with a history of serious hypersensitivity to amoxicillin, clavulanate or other beta-lactam antibiotics such as penicillins or cephalosporins.
• It is contraindicated in patients with a previous history of cholestatic jaundice or hepatic dysfunction associated with amoxicillin/clavulanate.
• Amoxicillin-containing medicines can cause a rash in patients with infectious mononucleosis.
• Monitor for significant diarrhea during or following antibiotic treatment.
• Patients with hepatic impairment may require appropriate medical monitoring.
• Unnecessary antibiotic use can contribute to antimicrobial resistance.
• The 200 mg/28.5 mg per 5 mL formulation should not be treated as interchangeable with other amoxicillin/clavulanate suspension strengths, because the clavulanic-acid content differs between formulations.

Moxymul CV 228.5 Storage

Store Moxymul CV 228.5 according to the conditions specified on the approved product packaging.

• Keep the dry syrup container properly closed.
• Protect from excessive heat and moisture.
• Keep out of reach of children.
• After reconstitution, follow the product label for storage conditions and discard period.
• Do not use the product after its expiry date.

Why Choose Moxymul CV 228.5 by Amcare Pharmaceuticals?

Moxymul CV 228.5 provides a pediatric oral-suspension formulation containing Amoxicillin 200 mg + Clavulanic Acid 28.5 mg per 5 mL.