Moxymul CV 457 – Amoxicillin 400 mg + Clavulanic Acid 57 mg Dry Syrup

Moxymul CV 457 by Amcare Pharmaceuticals is an oral antibacterial dry syrup containing Amoxicillin 400 mg + Clavulanic Acid 57 mg per 5 mL of reconstituted suspension. It is supplied as a dry powder for oral suspension and is intended for use in children when prescribed by a qualified healthcare professional.

The 400 mg/57 mg per 5 mL strength is an established amoxicillin/clavulanate oral-suspension formulation.

Composition of Moxymul CV 457

Each 5 mL of reconstituted suspension contains:

• Amoxycillin Trihydrate I.P. equivalent to Amoxycillin — 400 mg
• Potassium Clavulanate Diluted I.P. equivalent to Clavulanic Acid — 57 mg
• Excipients — q.s.
• Flavoured Base — q.s.

Moxymul CV 457 Product Details

Moxymul CV 457 Uses

Amoxicillin/clavulanate oral suspension is used for susceptible bacterial infections. Labelled indications for this combination include:

• Lower respiratory tract infections
• Acute bacterial otitis media
• Bacterial sinusitis
• Skin and skin-structure infections
• Urinary tract infections

The medicine should be used when a bacterial infection is suspected or confirmed and the organism is considered susceptible.

Lower Respiratory Tract Infections

Moxymul CV 457 may be prescribed for certain susceptible bacterial infections affecting the lower respiratory tract.

Acute Bacterial Otitis Media

Amoxicillin/clavulanate is used for certain bacterial middle-ear infections, including infections involving beta-lactamase-producing organisms.

Bacterial Sinusitis

The combination may be prescribed for certain susceptible bacterial sinus infections.

Skin and Skin-Structure Infections

Amoxicillin/clavulanate may be used for certain susceptible bacterial infections involving the skin and related structures.

Urinary Tract Infections

The combination has labelled use for certain susceptible bacterial urinary tract infections.

Benefits of Moxymul CV 457

• Contains Amoxicillin 400 mg + Clavulanic Acid 57 mg per 5 mL.
• Pediatric oral-suspension dosage form.
• Dry syrup format allows preparation before administration.
• Flavoured formulation designed for oral administration.
• Clavulanic acid inhibits certain beta-lactamase enzymes that can reduce the activity of amoxicillin.
• Provides antibacterial activity against susceptible bacteria.

How Does Moxymul CV 457 Work?

Amoxicillin 400 mg

Amoxicillin is a penicillin-class antibacterial that interferes with bacterial cell-wall synthesis, inhibiting the growth of susceptible bacteria.

Clavulanic Acid 57 mg

Clavulanic acid is a beta-lactamase inhibitor. It inhibits certain bacterial beta-lactamase enzymes, helping protect amoxicillin from enzymatic degradation and extending its activity against certain beta-lactamase-producing bacteria.

Moxymul CV 457 Dosage & Administration

Moxymul CV 457 should be administered to children only according to the dose prescribed by a qualified healthcare professional.

Pediatric dosing is determined according to factors such as:

• Body weight
• Age
• Type and severity of infection
• Kidney function
• Susceptibility of the causative organism
• Clinical response

The prescribing information bases pediatric dosing on the amoxicillin component.

Do not change the dose or duration of treatment without medical advice.

How to Prepare Moxymul CV 457 Dry Syrup

The product shown is supplied as dry syrup with sterile water.

1. Follow the reconstitution instructions supplied with the product.
2. Add the specified quantity of sterile water as directed.
3. Close the bottle securely.
4. Shake thoroughly until the powder is evenly dispersed.
5. Use the prepared suspension according to the doctor’s instructions.
6. Shake well before each administration.

The exact amount of water, storage conditions and discard period after reconstitution should follow the approved product label.

Moxymul CV 457 Side Effects

Possible adverse effects associated with amoxicillin/clavulanate include:

• Diarrhea
• Nausea
• Vomiting
• Skin rash
• Abdominal discomfort

Serious allergic reactions, severe skin reactions, liver-related adverse effects and antibiotic-associated diarrhea can also occur.

Seek prompt medical attention if the child develops breathing difficulty, facial swelling, severe rash, persistent/severe diarrhea, jaundice or other serious symptoms.

Moxymul CV 457 Precautions & Warnings

• Do not use in patients with a history of serious hypersensitivity to amoxicillin, clavulanate or other beta-lactam antibiotics such as penicillins or cephalosporins.
• It is contraindicated in patients with a previous history of cholestatic jaundice or hepatic dysfunction associated with amoxicillin/clavulanate.
• Amoxicillin-containing medicines can cause rash in patients with infectious mononucleosis.
• Monitor for significant diarrhea during or after antibiotic treatment.
• Patients with hepatic impairment may require appropriate medical monitoring.
• Antibiotics should be used only for bacterial infections that are proven or strongly suspected.
• The 400 mg/57 mg per 5 mL suspension should not be substituted with another amoxicillin/clavulanate suspension strength without medical direction because the clavulanate content differs between formulations.

Moxymul CV 457 Storage

Store Moxymul CV 457 according to the storage instructions provided on the approved product packaging.

• Keep the dry syrup container properly closed.
• Protect from excessive heat and moisture.
• Keep out of reach of children.
• After reconstitution, follow the product label for storage conditions and discard period.
• Do not use after the expiry date.

Why Choose Moxymul CV 457 by Amcare Pharmaceuticals?

Moxymul CV 457 provides a pediatric oral-suspension formulation containing Amoxicillin 400 mg + Clavulanic Acid 57 mg per 5 mL.