Temperate SP Tablets – Diclofenac Potassium 50 mg + Serratiopeptidase 15 mg + Paracetamol 325 mg

Temperate SP Tablets contain a combination of Diclofenac Potassium 50 mg, Serratiopeptidase 15 mg and Paracetamol 325 mg per film-coated tablet, as specified on the provided product artwork. The pack shown is 30 × 10 tablets.

Composition of Temperate SP Tablets

Product Information

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What are Temperate SP Tablets Used For?

Temperate SP Tablets are a combination medicine containing an NSAID (Diclofenac Potassium), an analgesic/antipyretic (Paracetamol) and Serratiopeptidase, an enzyme used in some formulations for management of swelling and inflammatory symptoms.

The combination may be prescribed for the short-term symptomatic management of painful and inflammatory conditions, particularly where pain, inflammation and swelling are present together.

It may be used in conditions such as:

• Musculoskeletal pain
• Joint pain associated with inflammation
• Sprains and strains
• Sports-related injuries
• Soft-tissue inflammation
• Post-traumatic pain and swelling
• Dental pain and inflammation
• Post-operative pain and swelling
• Orthopaedic inflammatory conditions
• Other painful inflammatory conditions as determined by a physician

Temperate SP should be used according to a qualified healthcare professional’s prescription.

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How Does Temperate SP Work?

Temperate SP combines three components with complementary pharmacological roles.

Diclofenac Potassium → Anti-inflammatory + Analgesic action

Paracetamol → Analgesic + Antipyretic action

Serratiopeptidase → Enzyme component used in formulations for inflammatory swelling

Together, the formulation is intended to provide symptomatic management when pain, inflammation and swelling occur together.

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1. Diclofenac Potassium – 50 mg

Diclofenac potassium belongs to the non-steroidal anti-inflammatory drug (NSAID) class.

It helps reduce the production of prostaglandins involved in inflammatory processes.

Diclofenac may help reduce:

• Pain
• Inflammation
• Swelling
• Tenderness

Simplified mechanism:

Diclofenac → Reduced prostaglandin synthesis → Reduced inflammatory response → Reduced pain and swelling

Diclofenac therefore provides the primary anti-inflammatory and analgesic component of Temperate SP.

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2. Paracetamol – 325 mg

Paracetamol is an analgesic and antipyretic medicine.

It contributes additional pain-relieving activity and can help reduce fever.

Simplified action:

Paracetamol → Analgesic/antipyretic action → Reduced pain and fever

The inclusion of paracetamol complements the analgesic activity of diclofenac.

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3. Serratiopeptidase – 15 mg

Serratiopeptidase is a proteolytic enzyme used in some pharmaceutical formulations intended to support management of inflammatory swelling.

It is commonly included in combination products used in areas such as:

• Orthopaedics
• Dentistry
• General surgery
• Traumatic injuries
• Soft-tissue inflammation

For your product page, it is safer to describe serratiopeptidase as an enzyme component used for inflammatory and swelling-related symptomatic support, rather than making claims that it directly “dissolves blood clots” or “cures inflammation.”

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Combined Action of Temperate SP

The three components have complementary roles:

Overall formulation

Pain + Inflammation + Swelling

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Diclofenac + Serratiopeptidase + Paracetamol

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Symptomatic relief of pain and inflammatory swelling

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Therapeutic Benefits / Role of Temperate SP

1. Pain Relief

Diclofenac and paracetamol provide complementary analgesic activity for the management of selected painful conditions.

2. Anti-inflammatory Support

Diclofenac helps reduce inflammation associated with various musculoskeletal and inflammatory conditions.

3. Swelling-Related Support

Serratiopeptidase is included as an enzyme component in formulations intended to support management of inflammatory swelling.

4. Fever Reduction

Paracetamol provides antipyretic activity when fever accompanies a painful condition.

5. Musculoskeletal Support

The combination may be prescribed for painful inflammatory conditions involving muscles, joints and soft tissues.

6. Post-Traumatic Symptomatic Management

The combination may be used for selected injuries where pain, inflammation and swelling occur together.

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Common Clinical Applications

1. Musculoskeletal Pain

Musculoskeletal injuries and inflammatory conditions may produce:

• Pain
• Swelling
• Tenderness
• Stiffness
• Restricted movement

Temperate SP may be prescribed for symptomatic relief in appropriate patients.

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2. Joint Pain

Inflammatory joint conditions can result in:

• Joint pain
• Swelling
• Stiffness
• Reduced mobility

Diclofenac provides anti-inflammatory and analgesic activity, while paracetamol provides additional analgesic action.

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3. Sprains and Strains

Sprains and strains may produce localized:

• Pain
• Swelling
• Inflammation
• Tenderness

Temperate SP may be prescribed for short-term symptomatic management when considered appropriate by the physician.

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4. Sports-Related Injuries

Sports injuries can involve soft-tissue inflammation, pain and swelling.

The combination may be used as part of physician-directed symptomatic treatment.

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5. Dental Pain & Inflammation

Dental procedures and inflammatory dental conditions can produce pain and swelling.

Temperate SP may be prescribed for appropriate patients for short-term symptomatic management.

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6. Post-Operative Pain & Swelling

Following certain surgical or dental procedures, patients may experience pain and local swelling.

A combination containing an NSAID, paracetamol and serratiopeptidase may be prescribed depending on the clinical situation.

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Suggested Use

Temperate SP Tablets should be taken only according to the dosage prescribed by a qualified healthcare professional.

The appropriate dose and treatment duration depend on:

• Type and severity of pain
• Patient age
• Medical history
• Kidney function
• Liver function
• Gastrointestinal history
• Cardiovascular risk
• Other medicines being used

Since the provided artwork does not specify a dosing schedule, an exact number of tablets per day should not be invented for the product page.

Administration

• Take orally with water.
• Follow the physician’s prescribed dosage.
• Do not exceed the recommended dose.
• Use for the duration prescribed by the healthcare professional.
• Do not combine with another diclofenac-containing medicine unless specifically advised.
• Check other medicines for paracetamol/acetaminophen content.

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Possible Side Effects

Temperate SP may cause adverse effects, particularly because it contains diclofenac.

Possible side effects may include:

• Nausea
• Vomiting
• Indigestion
• Abdominal discomfort
• Heartburn
• Diarrhea
• Constipation
• Headache
• Dizziness
• Skin rash

Individual response can vary.

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Important Serious Side Effects

Diclofenac-containing medicines can rarely cause serious adverse reactions, including:

• Gastrointestinal bleeding
• Gastric or intestinal ulceration
• Gastrointestinal perforation
• Severe allergic reactions
• Liver injury
• Kidney injury
• Fluid retention
• Increased blood pressure
• Cardiovascular events
• Serious skin reactions

Patients should seek medical attention if serious or unusual symptoms occur.

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Precautions & Warnings

1. Gastrointestinal Precautions

Diclofenac can increase the risk of gastrointestinal:

• Ulceration
• Bleeding
• Perforation

Patients with a history of peptic ulcer disease or gastrointestinal bleeding should inform their physician before using the medicine.

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2. Cardiovascular Precautions

NSAIDs such as diclofenac can increase the risk of serious cardiovascular events.

Particular caution may be required in patients with:

• Heart disease
• High blood pressure
• Previous stroke
• Cardiovascular risk factors

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3. Kidney Precautions

Diclofenac may affect kidney function, particularly in susceptible patients.

Patients with kidney disease should consult their physician before using Temperate SP.

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4. Liver Precautions

Because the product contains both diclofenac and paracetamol, appropriate caution is required in patients with liver disease.

Patients should also avoid taking multiple paracetamol-containing medicines without medical advice.

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Paracetamol-Related Precaution

Temperate SP contains Paracetamol 325 mg.

Patients should check other medicines they are taking for paracetamol/acetaminophen to avoid accidentally exceeding the recommended total intake.

Excessive paracetamol intake can cause serious liver injury.

Particular caution is appropriate in patients with:

• Liver disease
• High alcohol consumption
• Malnutrition
• Multiple paracetamol-containing medicines

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Serratiopeptidase-Related Precautions

Patients should inform their healthcare professional if they:

• Have a bleeding disorder
• Take anticoagulant medicines
• Take antiplatelet medicines
• Are scheduled for surgery
• Have a history of unusual bleeding

The complete safety profile of combination products should be evaluated according to the approved formulation and prescribing information.

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Drug & Medicine Interactions

Patients should inform their healthcare professional about all medicines they take.

Particular attention may be required with:

• Other NSAIDs
• Aspirin
• Anticoagulants
• Antiplatelet medicines
• Corticosteroids
• ACE inhibitors
• ARBs
• Diuretics
• Medicines affecting kidney function
• Methotrexate
• Lithium
• Digoxin
• Other paracetamol-containing medicines

Important

Do not take Temperate SP together with another diclofenac-containing medicine or another NSAID unless specifically advised by a healthcare professional.

Also check other medicines for paracetamol/acetaminophen.

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Pregnancy & Breastfeeding

Pregnant or breastfeeding women should consult a healthcare professional before taking Temperate SP.

Diclofenac and other NSAIDs require particular consideration during pregnancy, especially later in pregnancy.

The decision to use the product should be based on the individual clinical situation and applicable prescribing information.

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Use in Elderly Patients

Older patients may have a greater risk of NSAID-associated:

• Gastrointestinal complications
• Kidney problems
• Cardiovascular complications
• Fluid retention

Therefore, medical supervision is recommended.

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Use in Kidney or Liver Disease

Patients with kidney or liver disease should inform their physician before using Temperate SP.

The physician may need to assess:

• Kidney function
• Liver function
• Other medicines
• Overall risk-benefit profile

before prescribing the medicine.

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When Should Medical Attention Be Sought?

Patients should seek prompt medical attention if they experience:

• Black or bloody stools
• Vomiting blood
• Severe abdominal pain
• Chest pain
• Difficulty breathing
• Facial or throat swelling
• Severe skin rash
• Yellowing of the skin or eyes
• Significant reduction in urine
• Unusual or severe bleeding

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Storage

Store Temperate SP Tablets:

• In a cool, dry place
• Away from direct sunlight
• Protected from excessive heat and moisture
• In the original packaging
• Out of reach of children

Follow the storage conditions printed on the final approved product packaging.

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Key Product Features

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Why Choose Temperate SP Tablets?

Temperate SP combines three components in a single oral dosage form:

• Diclofenac Potassium 50 mg – anti-inflammatory and analgesic activity
• Serratiopeptidase 15 mg – enzyme component used in swelling/inflammation-related formulations
• Paracetamol 325 mg – analgesic and antipyretic activity

The combination is designed for symptomatic management of selected painful and inflammatory conditions where pain and swelling may occur together.